Outline: - Patient presentation, impression, comprehensive jaw relation records - Wax-up, Fabrication of the provisional restoration - Fabrication of a DVT based planning and drilling template - Surgical procedures for inserting four implants in the mandible - Suturing and relining of the existing denture as a provisional restoration - After 12 weeks: Reentry and insertion of healing abutments - Harvesting a free gingiva graft to extend the attached gingiva - Verifying implant stability using Periotest - Reworking the existing denture to fit on the healing abutments - Impressioning with custom tray (pick-up technique) - Demonstrating the line finder to transfer face axis - Fabricating the three restorations with Locator® attachments, electroplated double crown, precision-milled bar - The matrix and retention parts of the Locator® system, transferring the Locator® abutments to the implants - Fabricating the electroplated copings, intraoral adhesively connecting the electroplated copings to the cast framework (passive fit), finishing and delivery - Removable restoration on a custom-milled bar, clinical and laboratory workflow, delivery - Maintaining implant-supported restorations

Outline: - Surgical procedures for anchoring a diagnostic guide - Inserting four provisional implants - Impression and bite registration, fabrication of the master cast - Tooth-setup for the temporary restoration - Registering the setup in a silicone index - Duplicating the setup in radiopaque resin for CT imaging - Implant planning using a 3D record of the CT image - Fabricating a transfer template based on the CAD treatment plan using the CAMLOG® Guide System - Inserting the guiding sleeves into the template - Fabricating the final restoration prior to inserting the implants - Vario SR abutments with Vario SR titanium copings for a passive fit - Fabricating a cast titanium framework to reinforce the restoration - Surgical procedures demonstrating the definitive implant insertion - Insertion of six implants for immediate loading - Providing a controlled-clearance fit between the implants and the denture base

Contents: - Patient presentation and esthetic analysis - Careful extraction of a non-salvageable tooth - Miniplast splint as a surgical template - Harvesting bone from the implant bed - Placing a CONELOG® implant at site 11 - Obtaining a corticospongeous bone cylinder at site 48 - Alveolar augmentation and reconstruction of the buccal bone lamella - Harvesting a connective-tissue graft - Tunneling the vestibular mucosa, various suturing techniques - Insertion of the provisional restorations - 3 months later: Preparing, impression and arbitrary transfer with a bite fork and facebow, temporary restoration - Master cast, new wax-up, determine the emergence profile - Fabricating a hybrid abutment, Scanning the custom abutment, on-screen crown design - Fabricating a zirconia abutment and a feldspathic ceramic veneer - Conditioning and adhesive attachment of the components, final intraoral check - Try in and adhesive cementation

Objectives: Anodic oxidation treatment of titanium surfaces is widely studied because of the rapid osseointegration and biocompatibility of the material, however there are few studies in animals. This study evaluated the osseointegration of micro-nano roughened titanium surface.
Methods: A total of 48 titanium implants (MegagenTM/®) were used. They were classified into four groups (n=12): machined surface (group M), resorbable blasting media (RBM) surface (group R), nano surface (nanotube formation on the machined surface) (group MA), and nano-micro surface (nanotube formation on the RBM surface) (group RA). The micro-roughened surface was produced by blasting the titanium surface with aluminium oxide, and the nano-roughened surface was produced by anodic oxidation at a constant voltage of 20 V for 10 minutes with a DC power supply (Fine Power F-3005TM/®, SG EMD, Anyang, Korea). The titanium implants were placed in the humerus of beagle dogs. After 12 weeks, they were removed. Humerus bone blocks were embedded in paraffin and stained using haematoxylin–eosin.
Results: Histological analysis of the bone block revealed no inflammation around implants. New bone formation was observed along the nano-micro titanium implant surfaces. After 12 weeks, lamellar bone was formed along the nano-micro titanium implant surfaces.
Conclusions: Micro-nano roughened titanium implants surfaces show good osseointegration.

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