Procedure: - Case evaluation - Incision technique - Implant placement - Membrane adjustment and fixation - Introduction of replacement material - Flap mobilization - Suture technique Contents: Implantation was desired for replacement of a missing upper canine tooth and the adjacent lateral incisor tooth. The initial case evaluation revealed a relatively narrow gap between these two teeth in addition to extensive hard and soft-tissue defects. We selected an incision technique that made it possible to do the augmentation work yet subsequently achieve a tension-free flap closure. Since the bony defect was large while the available space was limited, we had to go for the best possible compromise in regard to implant insertion. After the implants had been inserted, augmentation was carried out using a non-absorbable, titanium-reinforced membrane, bone replacement material, and an absorbable membrane. Extreme flap mobilization was needed to achieve flap closure. An optimal suture technique was used to complete the surgery.

Objectives: There is little consistency in the choice of appropriate animal models in bone research, where evaluating bone repair dynamics is a basic part of bone morphofunctional studies. Among the available models, rabbits have several advantages. The bone defect repair rate is mainly dependent on the size of the bone wound, and experimentally created osseous injuries for studying repair mechanisms should be wide enough to preclude spontaneous healing. This study aimed to assess bone healing histologically in rabbit mandible defects. Methods: Three adult male rabbits were used. Defects with diameters of 3mm and 6mm, and a depth of 1.5mm, were created by excision of the mandible cortex using a trephine. Defects were allowed to fill with blood and the overlying soft tissues were repaired. Postoperatively, the rabbits were given antibiotic and analgesic therapy. In order to assess osteogenic activity, vital fluorochromic bone markers were used. After 6 weeks surgery, the animals were euthanised and bone segments were dissected and processed for histological evaluation. Analysis was performed with a light microscope. Results: During the observation period, the animals were healthy and presented no signs of infection. Both sagittal and transverse sections showed the dynamic of injury healing. After 6 weeks, the 3-mm defect had completely healed without inflammation, with proliferation of fibrous connective tissue and a minimal amount of immature woven bone. The new bone contained numerous blood vessels and osteoblasts. The 6-mm defect did not fully heal. Bone repair tissue was characterised by woven fibres, consistent with immature primary bone, and primitive Haversian spaces. Conclusion: We investigated the kinetics of healing in different sizes of rabbit mandibular defects. The 6-mm defect was the critical-sized defect. This experimental model will allow evaluation of the effect of different biomaterials on the healing process, in terms of adequacy of tissue quantity and quality, as well as the osteoconductive and osteoinductive characteristics of the test materials.

Inhalt: - Parodontologische Erhaltungstherapie in regio 34 und 35 mit Regenerierung des Knochendefekts durch Auffüllung mit Knochenersatzmaterial, Abdeckung mit Kollagen-Membran, Nahtlegung. - Taschenbehandlung mit Kürettage. - Behandlung druck-belasteter Gingiva unter festsitzender kieferorthopädischer Apparatur. - Inzision eines Wangenbändchens zur Entlastung der Gingiva zur Beseitigung einer Gingivarezession.